Optic Neuritis

NOTE: This pathway is intended for use in patients where there is a high clinical suspicion for vision symptoms to be secondary to optic nerve dysfunction resulting in optic neuritis/neuropathy. Questions are designed to help differentiate between the different etiologies for this. Inflammation of the optic nerve is a commonly associated with multiple sclerosis (as a presenting symptom or during the course of the disease), however, many other conditions may cause optic nerve dysfunction which can often be elicited through a comprehensive history.

Last updated 8/28/2026

Vision Symptoms

Autoimmune - multiple sclerosis (MS)/neuromyelitis optica (NMO)/myelin oligodendrocyte glycoprotein associated disease (MOGAD)/ neurosarcoidosis/other

Infectious

Nutritional

Toxic

Other

Diagnostic Evaluation

Optic Neuritis | Neurology Navigator