New onset weakness

NOTE: This pathway should be utilized in patients presenting with acute onset and/or rapidly progressive weakness. History taking should focus on identifying the extent of weakness, presence or absence of other neurologic symptoms, temporal progression of symptoms, identification of antecedent triggers, and associated conditions. Weakness secondary to primary brain conditions are not included in this template.

Last updated 8/27/2026

Introduction

Symptoms

Antecedent triggers and associated conditions

Diagnostic evaluation

New onset weakness | Neurology Navigator